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World Journal of Gastroenterology. Use of oral ethinyl estradiol appears to be strongly associated with cardiovascular events 30 and should therefore be avoided as a mainstay therapy for patients A or B cup-size is typical This is a permanent change. The optimal ranges for estrogen apply only to individuals taking estradiol or an ester of estradiol , and not to those taking synthetic or other non-bioidentical preparations e. Abstract Introduction Some providers report concern for the safety of transgender hormone therapy HT. SERT expression has been shown to be reduced in individuals with major depression The extent of these changes and the time interval for maximum change varies across patients and may take up to 18 to 24 months to occur.
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